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MS Analysis
At CellMosaic, we analyze molecules using Electrospray Ionization (ESI) Mass Spectrometry and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry. We offer high-quality mass spectrometry analysis services at competitive rates for a wide range of analytes, including small molecules, peptides, oligonucleotides, proteins, antibodies, and their bioconjugates.
These services are available both as part of our custom bioconjugation workflows and for products generated using our Personalized Conjugation Kit (PerKit™). If you have used a PerKit™ and would like analysis of your final product, please contact us for a quote.
- Electrospray Ionization (ESI) Mass Spectrometry
ESI is a soft ionization technique that generates ions by transferring charged species from solution-phase droplets into the gas phase. Compared with traditional electron ionization (EI) and chemical ionization (CI) methods, ESI uses lower energy and is less destructive, making it especially suitable for fragile biomolecules such as peptides, proteins, oligonucleotides, and carbohydrates. Samples can be analyzed either by direct infusion, where the solution is introduced directly into the mass spectrometer, or by liquid chromatography-mass spectrometry (LC-MS), where components of a mixture are first separated prior to MS analysis. - Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry
MALDI is a laser-based soft ionization technique in which the sample is co-crystallized with a suitable matrix. Upon laser irradiation, the matrix absorbs laser energy and facilitates desorption and ionization of the analyte into the gas phase. MALDI-TOF offers high sensitivity while requiring only small sample quantities, making it particularly well suited for the analysis of peptides, proteins, oligonucleotides, and other biomolecules.
Please download and complete the Sample Submission Form with all required information. Email us a copy, and include a printed copy with your samples. Ship your samples with a cold pack via overnight or earliest available delivery.
