Product Description
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| Product Sheet | |
| SDS | COA-0290961 |
Doxorubicin is an anticancer drug on the World Health Organization's List of Essential Medicines (the most effective and safe medicines needed in a health system). Medical usage of Doxorubicin includes treatment of breast cancer, bladder cancer, kaposi’s sarcoma, lymphoma, and acute lymphocytic leukemia. It intercalates DNA and inhibits macromolecular biosynthesis. This fluorescein-doxorubicin conjugate was first designed and synthesized at CellMosaic® for our customers' usage of detecting doxorubicin or doxorubicin labeled compounds.
The product is sold as 1 vial of 1 mg (Cat#: CM62102-1MG), 5 vials of 1 mg (Cat#: CM62102-5MG), or 10 vials of 1 mg (Cat#: CM62102-10MG). For bulk orders, please contact us for a quote.
Application
- Fluorescent based assay for the quantitation and detection of doxorubicin-labeled biopolymers (ADC and PDC), doxorubicin prodrugs, and free doxorubicin.
- Indirect and competitive ELISA assay.
Chemical Information
- Chemical name: Fluorescein-Doxorubicin conjugate
- Chemical formula: C48H40N2O16S
- Molecular weight: 932.91; CAS number: N/A
Specification
- Physical appearance: orange powder; Storage temp.: -20 °C
- Purity: ≥ 93% by HPLC
Frequently Asked Questions:
The list below includes FAQs that are specific to this product.
Question: What is the solubility of the Fluorescein-dox conjugate?
Answer: This product is readily soluble in a mixed solvent of DMSO/water. We generally use 2:1 DMSO:water (v/v) and dissolve the product to 0.5-1 mg/mL.
Question: What is the thermostability of the product and how fast does the degradation process start after reaching higher temperatures? Do I need to worry about the product if the cold pack is no longer cold when we receive the compound?
Answer: This compound is very stable as lyophilized solid at room temperature (RT). We have not determined the stabilities of this compound at RT, but it was prepared and purified at RT. We have not seen any decomposition or noticed any stability issues over the past if stored in the dark. The compound can be shipped at RT; however, we use a cold pack primarily to prevent a temperature spike during transportation and do not expect the compound to be cold with the current package configuration.
If you can’t find the answer you’re looking for or need information on general topics, please visit the main Frequently Asked Questions (FAQs) section.
