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ADC Assay Reagents

To facilitate our customers’ ADC research beyond the ADC preparation and characterization, CellMosaic® commercializes a variety of pre-made drug conjugates for ADC in vitro and in vivo bioassay.

These include BSA, HRP, Biotinylated, Fluorescent Labeled, and other biopolymer conjugates. Most of these drug conjugates are designed with the same or similar linker and conjugation strategies matching our ADC kits.

  • CM52140: BSA-Deruxtecan Conjugate

    BSA-Deruxtecan Conjugate

    Download Documents Product Sheet SDS COA (Lot S479.S15.1018C) Deruxtecan is an Exatecan (Exa) derivative conjugated through a cleavable peptide linker. It is a highly potent topoisomerase I inhibitor with strong anticancer activity...

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  • Chemical Structure of BSA-MMAE Conjugate with VC-PAB (valine-citruline p-aminobenzylcarbamate) cathepsin B Cleavable Linker Example MALDI-TOF MS data of BSA-MMAE Conjugate with VC-PAB Linker

    BSA-MMAE Conjugate

    Download Documents Product Sheet SDS COA (Lot 072420) MMAE (monomethyl auristatin E) is an antimitotic agent that binds to tubulin and inhibits the assembly of microtubules. Mc-VC-PAB-MMAE is a thiol reactive derivative of MMAE that...

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  • CM52149: BSA-SN38 Conjugate Structure

    BSA-SN38 Conjugate

    Download Documents Product Sheet SDS COA (Lot S585.S8.0311E) SN38, the active metabolite of irinotecan, is a chemotherapeutic agent primarily used for colorectal cancer treatment. As a topoisomerase I inhibitor, SN38 interferes with DNA...

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  • chemical structure of HRP-MMAE (1:1) Conjugate

    HRP-MMAE (1:1) Conjugate

    Download Documents Product Sheet SDS COA (Lot S17P1.072820) MMAE (monomethyl auristatin E) is an antimitotic agent that binds tubulin and inhibits the assembly of microtubules. Mc-VC-PAB-MMAE is a thiol reactive derivative of MMAE that...

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  • Chemical structure of HRP-MMAE (1:2) Conjugate (Horseradish peroxidase-monomethyl auristatin E, 1:2)

    HRP-MMAE (1:2) Conjugate

    Download Documents Product Sheet SDS COA (Lot S17P2.072820) MMAE (monomethyl auristatin E) is an antimitotic agent that binds tubulin and inhibits the assembly of microtubules. Mc-VC-PAB-MMAE is a thiol reactive derivative of MMAE that...

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