Novokinin

Product Description

Novokin has high affinity for the AT2 receptor (Ki=7.35 uM). The peptide is designed based on the structure of ovokinin (2-7), a bioactive peptide derived from ovalbumin.

Chemical Information

• Chemical name: Novokinin
• Sequence: Arg-Pro-Leu-Lys-Pro-Trp (or RPLKPW)
• C-terminus: free acid;                   N-terminus: free amine
• Counter ion: trifluoroactate salt;    Chemical formula: C₃₉H₆₁N₁₁O₇
• Molecular weight: 795.97;           CAS number: 358738-77-9

Specification

• Physical appearance: lyophilized powder;         Storage temp.: -20 °C
• Purity: ≥99.9% by HPLC

References

1. Yamada Y, Yamauchi D, Yokoo M, Ohinata K, Usui H, Yoshikawa M. Biosci Biotechnol Biochem. 2008 Jan;72(1):257-9. Epub 2008 Jan 7.
2. Yamada Y, Yamauchi D, Usui H, Zhao H, Yokoo M, Ohinata K, Iwai M, Horiuchi M, Yoshikawa M. Peptides. 2008 Mar;29(3):412-8. Epub 2007 Dec 4.
3. Ohinata K, Fujiwata Y, Shingo F, Masaru I, Masatsugu H, Yoshikawa M. Peptides. 2009 Jun;30(6):1105-8. Epub 2009 Mar 24; 4. Yamada Y, Nobuyuki M, Hachiro U, Kunhiko O, Masaaki Y. Bioscience, biotechnology, and biochemistry 2002, 66(6), 1213-1217.