Product Description
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| Product Sheet | |
| SDS | COA_Lot#0630E |
CellMosaic’s Exatecan Control Set is a ready-to-use solution for in vitro research, formulated to simplify your workflow and minimize handling risks of this potent cytotoxic agent. Exatecan binds to tubulin and inhibits DNA topoisomerase 1, leading to apoptosis.
This control set contains 6 tubes of a 10 µM Exatecan solution in DMSO, a concentration suitable for most biological research and cell-based assays.
The 10 µM concentration is intentionally set within a safe, research-appropriate range for analytical studies, both quantitative and qualitative. Each tube is intended for a single experiment, enabling straightforward dilution (see product sheet Table 1 for suggested dilutions). The Exatecan solution is pre-formulated and stable at room temperature, requiring no preparation before use or dilution.
Drug Information
- Chemical name: Exatecan (DX-8951)
- Chemical formula:C24H22FN3O4
- Molecular weight: 435.45 Da CAS number:171335-80-1
- Mechanism of Action: Binds to topoisomerase I (Topo I)-DNA complexes via hydrogen bonding, preventing DNA relegation and inducing DNA damage and apoptosis.
- Activities: Anti-tumor.
Key Features of the Product
- Pre-formulated 10 µM stock in DMSO —no preparation needed.
- Convenient format: 6 single-use tubes for consistent results.
- Ideal for:
- Drug screening
- Cell-viability, proliferation and cytotoxicity assays
- Other qualitative and quantitative studies
- Sufficient volume for replicates.
