Product Description
CellMosaic’s Exatecan Control Set is a ready-to-use solution for in vitro research, formulated to simplify your workflow and minimize handling risks of this potent cytotoxic agent.
| Download Documents | |
|---|---|
| Product Sheet | |
| SDS | COA (Lot #0630E) |
Exatecan binds to tubulin and inhibits DNA topoisomerase 1, leading to apoptosis. This control set contains 6 tubes of a 10 µM Exatecan solution in DMSO, a concentration suitable for most biological research and cell-based assays.
The 10 µM concentration is intentionally set within a safe, research-appropriate range for analytical studies, both quantitative and qualitative. Each tube is intended for a single experiment, enabling straightforward dilution (see product sheet Table 1 for suggested dilutions). The Exatecan solution is pre-formulated and stable at room temperature, requiring no preparation before use or dilution.
Drug Information
- Chemical name: Exatecan (DX-8951)
- Chemical formula:C24H22FN3O4
- Molecular weight: 435.45 Da CAS number:171335-80-1
- Mechanism of Action: Binds to topoisomerase I (Topo I)-DNA complexes via hydrogen bonding, preventing DNA relegation and inducing DNA damage and apoptosis.
- Activities: Anti-tumor.
Key Features of the Product
- Pre-formulated 10 µM stock in DMSO —no preparation needed.
- Convenient format: 6 single-use tubes for consistent results.
- Ideal for:
- Drug screening
- Cell-viability, proliferation and cytotoxicity assays
- Other qualitative and quantitative studies
- Sufficient volume for replicates.
Frequently Asked Questions:
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