Product Description
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| Product Sheet | |
| SDS | COA_Lot#0630E |
CellMosaic’s SN38 Control Set is a ready-to-use solution for in vitro research, formulated to simplify your workflow and minimize handling risks of this potent cytotoxic agent. SN38 (7-ethyl-10-hydroxycamptothecin) is a metabolite of irinotecan, a highly potent cytotoxic compound that inhibits DNA topoisomerase 1, leading to apoptosis.
This control set contains 6 tubes of a 10 µM SN38 solution in DMSO, a concentration suitable for most biological research and cell-based assays.
The 10 µM concentration is intentionally set within a safe, research-appropriate range for analytical studies, both quantitative and qualitative. Each tube is intended for a single experiment, enabling straightforward dilution (see product sheet Table 1 for suggested dilutions). The SN38 solution is pre-formulated and stable at room temperature, requiring no preparation before use or dilution.
Drug Information
- Chemical name:SN38 (7-ethyl-10-hydroxycamptothecin)
- Chemical formula:C22H20N2O5
- Molecular weight: 392.42 Da CAS number:86639-52-3
- Mechanism of Action: Inhibition of topoisomerase I leads to inhibition of both DNA replication and transcription.
- Activities: Anti-neoplastic
Key Features of the Product
- Pre-formulated 10 µM stock in DMSO —no preparation needed.
- Convenient format: 6 single-use tubes for consistent results.
- Ideal for:
- Drug screening
- Cell-viability, proliferation and cytotoxicity assays
- Other qualitative and quantitative studies
- Sufficient volume for replicates.
