Publications and Citations
Publications from CellMosaic
Yumei Huang, Shuyan Chen, Binyuan Sun, Amanda Griffin, Nathanial Sweet, Mingqian Feng, Mitchell Ho. Synthesis and evaluation of sugar alcohol based molecules for drug conjugation and delivery [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 755. https://doi.org/10.1158/1538-7445.AM2018-755
Collaboration with University of New Mexico: Since 2019, CellMosaic has helped Professor Frietze's lab design and synthesize key peptide and drugs of abuse conjugate for vaccine generation.
Isabella G. Romano, Susan B. Core, Naomi R. Lee, Curtis Mowry, Koen K.A. Van Rompay, Yumei Huang, Bryce Chacherain, Kathryn M. Frietze, "A bacteriophage virus-like particle vaccine against oxycodone elicits high-titer and long-lasting antibodies that sequester drug in the blood" Vaccines 2024, 2(3), 471-480.
Isabella G. Romano, Brandi Johnson-Weaver, Susan B. Core, Andzoa N Jamus, Marcus Brackeen, Bruce Blough, Subhakar Dey, Yumei Huang, Herman Staats, William C Wetsel, Bryce Chacherain, Kathryn M. Frietze, "Two doses of QB virus-like particle vaccines elicit protective antibodies against heroin and fentanyl" NPJ Vaccines 2025, 2025 Mar 28;10(1):57. doi: 10.1038/s41541-025-01105-0.
Selected Customer Citations Utilizing CellMosaic's Services and Products
Services
Bioasis projects: In 2013, CellMosaic prepared numerous single-labeled melanotransferrin protein-antibody conjugates, melanotransferrin peptide-antibody conjugates with defined loading, Peptide-HRP-dye triconjugate, peptide-antibody-dye triconjugates for their pre-clinical research.
George Thom, Mei-Mei Tian, Jon P Hatcher, Natalia Rodrigo, Matthew Burrell, Ian Gurrell, Timothy Z Vitalis, Thomas Abraham, Wilfred A Jefferies, Carl I Webster, Reinhard Gabathuler, "A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model" J Cereb Blood Flow Metab 2019 39(10), 2074-2088. doi: 10.1177/0271678X18772998. Epub 2018 May 30.
Kit Products
CM11409 (Antibody MMAE Conjugation Kit with VC-PAB Linkage)
Lofgren, K. A.; Sreekumar, S.; Jenkins, C. E., Jr.; Ernzen, K. J.; Kenny, P. A. Anti-tumor efficacy of an MMAE-conjugated antibody targeting cell surface TACE/ADAM17-cleaved Amphiregulin in breast cancer. Antibody Therapeutics 2021, 4(4), 252-261. DOI: 10.1093/abt/tbab026
Kierkels, G. J. J.; van Diest, E.; Hernández-López, P.; Scheper, W; de Bruin, A.C.M.; Frijlink, E; Aarts-Riemens, T; van Dooremalen, S. F. J.; Beringer, D. X.; Oostvogels, R; Kramer, L.; Straetemans, T.; Uckert, W.; Sebestyén, Z.; Kuball, J. Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells Molecular Therapy-Methods & Clinical Development 2021, 22, 388-400. DOI:10.1016/j.omtm.2021.06.011
Parameswaran, N.; Luo L.; Zhang, L.; Chen, J.; DiFilippo, F. P.; Androjna, C.; Fox, D. A.; Ondrejka, S. L.; Hsi, E. D.; Jagadeesh, D.; Lindner, D. J.; Lin, F. CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma Leukemia 2023, 37, 2050-2057. DOI:10.1038/s41375-023-01997-8
Zhang, L; Luo, L.; Chen, J. Y.; Singh, R.; Baldwin III, W. M.; Fox, D. A.; Lindner, D. J.; Martin, D. F.; Caspi, R. R.; Lin, F. A CD6-targeted antibody-drug conjugate as a potential therapy for T cell–mediated disorders JCI Insight 2023, 8(23), e172914. DOI:10.1172/jci.insight.172914
Sun, Z.; Chu, X.; Adams C.; Ilina, T. V.; Guerrero, M.; Lin, G.; Chen, C.; Jelev, D.; Ishima, R.; Li, W.; Mellors, J. W.; Calero, G.; Dimitrov, D. S. Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate Molecular Therapy-Oncolytics 2023, 31,100726. DOI: 10.1016/j.omto.2023.09.002
Hou, J; Uejima, T.; Tanaka, M.; Lee Son, Y.; Hanada, K.; Kukimoto-Niino, M.; Yamaguchi, S.; Hashimoto, S.; Yokoyama, S.; Takemori, T.; Saito, T.; Shirouzu, M.; Kondo, T. EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells Neuro-Oncology 2024, 27(3), 682-694. DOI: 10.1093/neuonc/noae226
CM11408 (Antibody SN38 Conjugation Kit)
Micalizzi, D. S.; Che, D.; Nicholson, B. T.; Edd, J. F.; Desai, N.; Lang, E. R.; Toner, M.; Maheswaran, S.; Ting, D. T.; Haber, D. A. Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody. PNAS 2022, 119(43), e2209563119. DOI: 10.1073/pnas.2209563119
CM11431 Antibody Deruxtecan Conjugation Kit
Semenova, G.; Frank, S.; Dumpit, R.; Han, W.; Coleman, I.; Gulati, R.; Morrissey, C.; Haffner, M. C.; Nelson, P. S.; Lee, J. K. Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer, Ver. 1. bioRxiv September 11, 2025. DOI: 10.1101/2025.09.05.674562
CM52402 BSA-Peptide Conjugation Kit
Kleinman, A.; Torres, J.; Wang, B. Evaluation of antibiotic and peptide vaccine strategies for mirror bacterial infections, Ver. 1. bioRxiv October 12, 2025. DOI: 10.1101/2025.10.10.681688
CM52411 KLH-Peptide Conjugation Kit
Kleinman, A.; Torres, J.; Wang, B. Evaluation of antibiotic and peptide vaccine strategies for mirror bacterial infections, Ver. 1. bioRxiv October 12, 2025. DOI: 10.1101/2025.10.10.681688
CM53402 and CM53408 HRP Oligo Conjugation Kit (Single Label with Thiol Oligo)
Aviñó, A.; Cuestas-Ayllón, C.; Gutiérrez-Capitán, M.; Vilaplana, L.; Grazu, V.; Noé, V.; Balada, E.; Baldi, A.; Félix, A. J.; Aubets, E.; Valiuska, S.; Domínguez, A.; Gargallo, R. Eritja, R.; Marco M.-P.; Fernández-Sánchez, C.; Martínez de la Fuente, J.; Ciudad, C. J. Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA) International Journal of Molecular Sciences, 2022, 23(23), 15258. DOI: 10.3390/ijms232315258
Gutiérrez-Capitán, M.; Balada, E.; Aviñó A.; Vilaplana, L.; Galve, R.; Lacoma, A; Baldi, A.; Alcamí, A.; Noé, V.; Ciudad, C. J.; Eritja, R.; Marco, M.-P.; Fernández-Sánchez, C. Unraveling the Amplification-Fre Quantitative Detection of ViralRNA in Nasopharyngeal Swab Samples Using a Compact Electrochemical Rapid Test Device Analytical Chemistry, 2025, 97(22), 11863−11873. DOI: 10.1021/acs.analchem.5c01605
CM53403 AP Oligo Conjugation Kit (Single Label with Amine Oligo)
Schwartz, A. M.; Marcotte, H. A.; Johnson, C. N. Evaluation of Alternative Colony Hybridization Methods for Pathogenic Vibrios Foods 2023, 12(7), 147 DOI: 10.3390/foods12071472
CM71007 (SepSphere™ Small Molecule Alcohol Immobilization Kit)
Yang, F.; Zhang, D.; Jiang, H.; Ye, J.; Zhang, L.; Bagley, S. J.; Winkler, J; Gong, Y.; Fan, Y. Small-molecule toosendanin reverses macrophage-mediated immunosuppression to overcome glioblastoma resistance to immunotherapy Science Translational Medicine 2023, 15(683), eabq3558. DOI: 10.1126/scitranslmed.abq3558
Reagent Products
CM16001 (Curcumin-beta-D-Glucuronide MS Standard)
Chen W.; Fan-Harvard, P.; Yee, L. D.; Cao, Y.; Stoner, G. D.; Chan, K. K.; Liu, Z. A liquid chromatography-Tandem mass spectrometric method for quantification of curcumin-O-glucuronide and curcumin in human plasma. Journal of Chromatography B 2012, 900, 89-93. DOI: 10.1016/j.jchromb.2012.05.026
Cao Y.; Xu, R. X.; Liu, Z. A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry. Journal of Chromatography B. 2014, 949-950, 70-78. DOI: 10.1016/j.jchromb.2013.12.039
CM29101 (SepSphere™ Alprenolol Agarose)
Salom, D.; Padayatti, P. S.; Palczewski, K. Crystallization of G protein-coupled receptors Methods Cell Biology 2013, 117, 451-468. DOI: 10.1016/B978-0-12-408143-7.00024-4
Cheong, H. I.; Asosingh, K.; Stephens, O. R.; Queisser, K. A.; Xu, W.; Willard, B.; Hu, B.; Dermawan, J. K. T.; Stark, G. R.; Naga Prasad, S. V.; Erzurum, S. C. Hypoxia sensing through β-adrenergic receptors JCI Insight 2016, 1(21), e90240. DOI: 10.1172/jci.insight.90240
CM61002 (Biotin-Alprenolol Conjugate)
Rose, J. A.; Wanner, N.; Cheong, H. I.; Queisser, K.; Barrett, P.; Park, M.; Hite, C.; Naga Prasad, S. V.; Erzurum, S.; Asosingh, K. Flow Cytometric Quantification of Peripheral Blood Cell β-Adrenergic Receptor Density and Urinary Endothelial Cell-Derived Microparticles in Pulmonary Arterial Hypertension PLoS One 2016, 11(6), e0156940, DOI: 10.1371/journal.pone.0156940
Christoffersson, G.; Ratliff, S. S.; von Herrath, M. G. Interference with pancreatic sympathetic signaling halts the onset of diabetes in mice Science Advances: Immunology, 2020, 6(35), eabb2878 DOI: 10.1126/sciadv.abb2878
Mohiuddin, I. S..; Wei, S.-J.; Yang, I.-H.; Martinez, G. M..; Yang, S.; Cho, E. J.; Dalby, K. N.; Kang, M. H. Development of cell-based high throughput luminescence assay for drug discovery in inhibiting OCT4/DNA-PKcs and OCT4–MK2 interactions Biotechnology and Bioengineering 2021, 118(5): 1987–2000 DOI: 10.1002/bit.27712
Kaminski, T.; Zhdanov, V. P.; Höök, F. Single-molecule Dynamic In-Solution Inhibition Assay: A Method for Full Kinetic Profiling of Drug Candidate Binding to GPCRs in Native Membranes bioRxiv September 16, 2021. DOI: 10.1101/2021.09.16.460640
CM92004 SEC (Gel Filtration) HPLC Protein Standard (7 components, Lyophilized)
Shon, H.; Matveeva, E. A.; Jull, E. C.; Hu, Y.; Coupet, T. A.; Lee, Y.-S. Evidence Supporting Substrate Channeling between Domains of Human PAICS: A Time-Course Analysis of 13C‑Bicarbonate Incorporation Biochemistry 2022, 61(7), 575-582 DOI: 10.1021/acs.biochem.1c00803
Collier, G.; Roovers A. L.; Hulleman, J. D. A spectrum of cysteine mutations in fibulin-3 highlight its disulfide bonding complexity and potential to induce ER stress Scientific Reports 2025, 15, 30028 DOI: 10.1038/s41598-025-14561-4
Azam, M.S.; Missiakas, D.; The signal peptide of staphylococcal protein A alters the multimeric states of PepV Microbiology Spectrum 2025, e01778-25 DOI: 10.1128/spectrum.01778-25
CM92005 SEC (Gel Filtration) HPLC Low Molecular Weight (LMW) Protein Standard
Oh, H. B.; Yoon, S. Crystal structures of Campylobacter jejuni CadF reveal a potential role for the arginine residue R268 in peptidoglycan recognition and pocket formation Scientific Reports 2025, 15, 36733 DOI: 10.1038/s41598-025-20604-7