Size exclusion chromatography (SEC) HPLC is suitable for analyzing mixtures of biopolymers, separating the components according to size. It can be used to determine the approximate molecular weight of the molecules. In the case of bioconjugate analysis such as antibody drug conjugate, it can be used to assess the amount of unlabeled molecules and degree of bioconjugate aggregation in a sample. A standard pdf file of the HPLC profile will be supplied.
Per sample charge.
Setup fee of $250 applies per batch analysis. Setup fee will be waived if the conjugate is made using CellMosaic's kit.
Standard services is 1-3 days.
Sample submission for biopolymers, bioconjugates, ADCs:
1) Dilute your samples in PBS buffer to 1 mg/mL, and then transfer minimum 50 μL of the diluted solution to a 500 μL micro-centrifuge tube. Label the vial properly.
2) Ship your samples with a cold pack for overnight delivery.
For analysis of bioconjugates such as antibody drug conjugates, always ship a sample of un-labeled biopolymer for analysis at the same time.